GLOBAL PERSPECTIVE OF ENVIRONMENTAL DISTRIBUTION AND DIVERSITY OF PERKINSEA (ALVEOLATA) EXPLORED BY A META-ANALYSIS OF EDNA SURVEYS

Global perspective of environmental distribution and diversity of Perkinsea (Alveolata) explored by a meta-analysis of eDNA surveys

Abstract Perkinsea constitutes a lineage within the Alveolata eukaryotic superphylum, mainly composed of parasitic organisms.Some described species represent significant ecological and economic threats due to their invasive ability and pathogenicity, which can lead to mortality events.However, the genetic diversity of these described species is jus

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HLA Class II Defects in Burkitt Lymphoma: Bryostatin-1-Induced 17 kDa Protein Restores CD4+ T-Cell Recognition

While the defects in HLA class I-mediated Ag presentation by Burkitt lymphoma (BL) have been well documented, CD4+ T-cells are also poorly stimulated by HLA class II Ag presentation, and the reasons underlying this defect(s) have not yet been fully resolved.Here, we show that BL cells are deficient in their ability to optimally stimulate CD4+ T cel

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